The path of DNA in the kinetochore
نویسندگان
چکیده
Membrane biophysics is a vast field, in which life uses all of the physical forces and laws to organize physiological processes. The simple physics of the phospholipid bilayer often dominates the structure of the membrane to provide compartmentalization of cellular space — proteins work within the constraints of the bilayer to catalyze lipid metabolism, bend membranes, transport impermeant substances, organize microdomains, and many other essential processes of life.
منابع مشابه
Chromatin containing CENP-A and α-satellite DNA is a major component of the inner kinetochore plate
The pathway of molecular interactions leading to kinetochore assembly on mammalian chromosomes is unknown. Kinetochores could be specified by structural features of centromeric satellite DNA [1-3] or by specific DNA sequences, analogous to budding yeast centromeres, interspersed in centromeric satellite DNA arrays [4,5]. Alternatively, kinetochores could be epigenetic structures that replicate ...
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عنوان ژورنال:
- Current Biology
دوره 16 شماره
صفحات -
تاریخ انتشار 2006